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Targeting the MYCN-PARP-DNA Damage Response Pathway in Neuroendocrine Prostate Cancer

PURPOSE: We investigated MYCN-regulated molecular pathways in castration-resistant prostate cancer (CRPC) classified by morphological criteria as adenocarcinoma or neuroendocrine to extend the molecular phenotype, establish driver pathways, and identify novel approaches to combination therapy for NE...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Zhang, Wei, Liu, Bo, Wu, Wenhui, Li, Likun, Broom, Bradley M., Basourakos, Spyridon P., Korentzelos, Dimitrios, Luan, Yang, Wang, Jianxiang, Yang, Guang, Park, Sanghee, Azad, Abul Kalam, Cao, Xuhong, Kim, Jeri, Corn, Paul G., Logothetis, Christopher J., Aparicio, Ana M., Chinnaiyan, Arul M., Navone, Nora, Troncoso, Patricia, Thompson, Timothy C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823274/
https://ncbi.nlm.nih.gov/pubmed/29138344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1872
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