Enzalutamide and CXCR7 inhibitor combination treatment suppresses cell growth and angiogenic signaling in castration‐resistant prostate cancer models

Previous studies have shown that increased levels of chemokine receptor CXCR7 are associated with the increased invasiveness of prostate cancer cells. We now show that CXCR7 expression is upregulated in VCaP and C4‐2B cells after enzalutamide (ENZ) treatment. ENZ treatment induced apoptosis (sub‐G1)...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Luo, Yong, Azad, Abul Kalam, Karanika, Styliani, Basourakos, Spyridon P., Zuo, Xuemei, Wang, Jianxiang, Yang, Luan, Yang, Guang, Korentzelos, Dimitrios, Yin, Jianhua, Park, Sanghee, Zhang, Penglie, Campbell, James J., Schall, Thomas J., Cao, Guangwen, Li, Likun, Thompson, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Cancer Therapy and Prevention
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867246/
https://ncbi.nlm.nih.gov/pubmed/29277895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31237
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