Enzalutamide and CXCR7 inhibitor combination treatment suppresses cell growth and angiogenic signaling in castration‐resistant prostate cancer models

Previous studies have shown that increased levels of chemokine receptor CXCR7 are associated with the increased invasiveness of prostate cancer cells. We now show that CXCR7 expression is upregulated in VCaP and C4‐2B cells after enzalutamide (ENZ) treatment. ENZ treatment induced apoptosis (sub‐G1)...

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Bibliografiske detaljer
Udgivet i:Int J Cancer
Main Authors: Luo, Yong, Azad, Abul Kalam, Karanika, Styliani, Basourakos, Spyridon P., Zuo, Xuemei, Wang, Jianxiang, Yang, Luan, Yang, Guang, Korentzelos, Dimitrios, Yin, Jianhua, Park, Sanghee, Zhang, Penglie, Campbell, James J., Schall, Thomas J., Cao, Guangwen, Li, Likun, Thompson, Timothy C.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Cancer Therapy and Prevention
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867246/
https://ncbi.nlm.nih.gov/pubmed/29277895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31237
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