Targeting the MYCN-PARP-DNA Damage Response Pathway in Neuroendocrine Prostate Cancer

PURPOSE: We investigated MYCN-regulated molecular pathways in castration-resistant prostate cancer (CRPC) classified by morphological criteria as adenocarcinoma or neuroendocrine to extend the molecular phenotype, establish driver pathways, and identify novel approaches to combination therapy for NE...

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書誌詳細
出版年:Clin Cancer Res
主要な著者: Zhang, Wei, Liu, Bo, Wu, Wenhui, Li, Likun, Broom, Bradley M., Basourakos, Spyridon P., Korentzelos, Dimitrios, Luan, Yang, Wang, Jianxiang, Yang, Guang, Park, Sanghee, Azad, Abul Kalam, Cao, Xuhong, Kim, Jeri, Corn, Paul G., Logothetis, Christopher J., Aparicio, Ana M., Chinnaiyan, Arul M., Navone, Nora, Troncoso, Patricia, Thompson, Timothy C.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823274/
https://ncbi.nlm.nih.gov/pubmed/29138344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1872
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