Targeting the MYCN-PARP-DNA Damage Response Pathway in Neuroendocrine Prostate Cancer

PURPOSE: We investigated MYCN-regulated molecular pathways in castration-resistant prostate cancer (CRPC) classified by morphological criteria as adenocarcinoma or neuroendocrine to extend the molecular phenotype, establish driver pathways, and identify novel approaches to combination therapy for NE...

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Publicado en:Clin Cancer Res
Main Authors: Zhang, Wei, Liu, Bo, Wu, Wenhui, Li, Likun, Broom, Bradley M., Basourakos, Spyridon P., Korentzelos, Dimitrios, Luan, Yang, Wang, Jianxiang, Yang, Guang, Park, Sanghee, Azad, Abul Kalam, Cao, Xuhong, Kim, Jeri, Corn, Paul G., Logothetis, Christopher J., Aparicio, Ana M., Chinnaiyan, Arul M., Navone, Nora, Troncoso, Patricia, Thompson, Timothy C.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823274/
https://ncbi.nlm.nih.gov/pubmed/29138344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1872
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