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Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions
Maintenance of genomic stability is a critical determinant of cell survival and is necessary for growth and progression of malignant cells. Interstrand crosslinking (ICL) agents, including platinum-based agents, are first-line chemotherapy treatment for many solid human cancers. In malignant cells,...
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| 出版年: | Curr Med Chem |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471128/ https://ncbi.nlm.nih.gov/pubmed/27978798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867323666161214114948 |
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