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Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions
Maintenance of genomic stability is a critical determinant of cell survival and is necessary for growth and progression of malignant cells. Interstrand crosslinking (ICL) agents, including platinum-based agents, are first-line chemotherapy treatment for many solid human cancers. In malignant cells,...
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| Publicado no: | Curr Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5471128/ https://ncbi.nlm.nih.gov/pubmed/27978798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/0929867323666161214114948 |
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