PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal

The adrenal cortex undergoes remodeling during fetal and postnatal life. How zona reticularis emerges in the postnatal gland to support adrenarche, a process whereby higher primates increase prepubertal androgen secretion, is unknown. Using cell-fate mapping and gene deletion studies in mice, we sho...

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Bibliographic Details
Published in:JCI Insight
Main Authors: Dumontet, Typhanie, Sahut-Barnola, Isabelle, Septier, Amandine, Montanier, Nathanaëlle, Plotton, Ingrid, Roucher-Boulez, Florence, Ducros, Véronique, Lefrançois-Martinez, Anne-Marie, Pointud, Jean-Christophe, Zubair, Mohamad, Morohashi, Ken-Ichirou, Breault, David T., Val, Pierre, Martinez, Antoine
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821213/
https://ncbi.nlm.nih.gov/pubmed/29367455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98394
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