PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development

Adrenal cortex physiology relies on functional zonation, essential for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona fasciculata (ZF). The cortex undergoes constant cell renewal, involving recruitment of subcapsular progenitors to ZG fate and subsequent l...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Drelon, Coralie, Berthon, Annabel, Sahut-Barnola, Isabelle, Mathieu, Mickaël, Dumontet, Typhanie, Rodriguez, Stéphanie, Batisse-Lignier, Marie, Tabbal, Houda, Tauveron, Igor, Lefrançois-Martinez, Anne-Marie, Pointud, Jean-Christophe, Gomez-Sanchez, Celso E., Vainio, Seppo, Shan, Jingdong, Sacco, Sonia, Schedl, Andreas, Stratakis, Constantine A., Martinez, Antoine, Val, Pierre
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027289/
https://ncbi.nlm.nih.gov/pubmed/27624192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12751
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