PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development

Adrenal cortex physiology relies on functional zonation, essential for production of aldosterone by outer zona glomerulosa (ZG) and glucocorticoids by inner zona fasciculata (ZF). The cortex undergoes constant cell renewal, involving recruitment of subcapsular progenitors to ZG fate and subsequent l...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Drelon, Coralie, Berthon, Annabel, Sahut-Barnola, Isabelle, Mathieu, Mickaël, Dumontet, Typhanie, Rodriguez, Stéphanie, Batisse-Lignier, Marie, Tabbal, Houda, Tauveron, Igor, Lefrançois-Martinez, Anne-Marie, Pointud, Jean-Christophe, Gomez-Sanchez, Celso E., Vainio, Seppo, Shan, Jingdong, Sacco, Sonia, Schedl, Andreas, Stratakis, Constantine A., Martinez, Antoine, Val, Pierre
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027289/
https://ncbi.nlm.nih.gov/pubmed/27624192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12751
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