EZH2 is overexpressed in adrenocortical carcinoma and is associated with disease progression

Adrenal Cortex Carcinoma (ACC) is an aggressive tumour with poor prognosis. Common alterations in patients include constitutive WNT/β-catenin signalling and overexpression of the growth factor IGF2. However, the combination of both alterations in transgenic mice is not sufficient to trigger malignan...

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Publicat a:Hum Mol Genet
Autors principals: Drelon, Coralie, Berthon, Annabel, Mathieu, Mickael, Ragazzon, Bruno, Kuick, Rork, Tabbal, Houda, Septier, Amandine, Rodriguez, Stéphanie, Batisse-Lignier, Marie, Sahut-Barnola, Isabelle, Dumontet, Typhanie, Pointud, Jean-Christophe, Lefrançois-Martinez, Anne-Marie, Baron, Silvère, Giordano, Thomas J., Bertherat, Jérôme, Martinez, Antoine, Val, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095221/
https://ncbi.nlm.nih.gov/pubmed/27149985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw136
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