Analysis of the Role of Igf2 in Adrenal Tumour Development in Transgenic Mouse Models

Adrenal cortical carcinomas (ACC) are rare but aggressive tumours associated with poor prognosis. The two most frequent alterations in ACC in patients are overexpression of the growth factor IGF2 and constitutive activation of Wnt/β-catenin signalling. Using a transgenic mouse model, we have previou...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Drelon, Coralie, Berthon, Annabel, Ragazzon, Bruno, Tissier, Frédérique, Bandiera, Roberto, Sahut-Barnola, Isabelle, de Joussineau, Cyrille, Batisse-Lignier, Marie, Lefrançois-Martinez, Anne-Marie, Bertherat, Jérôme, Martinez, Antoine, Val, Pierre
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429465/
https://ncbi.nlm.nih.gov/pubmed/22952916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044171
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