Analysis of the Role of Igf2 in Adrenal Tumour Development in Transgenic Mouse Models

Adrenal cortical carcinomas (ACC) are rare but aggressive tumours associated with poor prognosis. The two most frequent alterations in ACC in patients are overexpression of the growth factor IGF2 and constitutive activation of Wnt/β-catenin signalling. Using a transgenic mouse model, we have previou...

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書誌詳細
主要な著者: Drelon, Coralie, Berthon, Annabel, Ragazzon, Bruno, Tissier, Frédérique, Bandiera, Roberto, Sahut-Barnola, Isabelle, de Joussineau, Cyrille, Batisse-Lignier, Marie, Lefrançois-Martinez, Anne-Marie, Bertherat, Jérôme, Martinez, Antoine, Val, Pierre
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429465/
https://ncbi.nlm.nih.gov/pubmed/22952916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044171
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