Transcriptional Control of Adrenal Steroidogenesis: NOVEL CONNECTION BETWEEN JANUS KINASE (JAK) 2 PROTEIN AND PROTEIN KINASE A (PKA) THROUGH STABILIZATION OF cAMP RESPONSE ELEMENT-BINDING PROTEIN (CREB) TRANSCRIPTION FACTOR

In the adrenal gland, adrenocorticotropin (ACTH) acting through the cAMP protein kinase (PKA) transduction pathway is the main regulator of genes involved in glucocorticoid synthesis. The prolactin (PRL) receptor is expressed in the adrenal cortex of most mammals, but experimental proof that PRL ens...

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Detalhes bibliográficos
Main Authors: Lefrancois-Martinez, Anne-Marie, Blondet-Trichard, Antonine, Binart, Nadine, Val, Pierre, Chambon, Céline, Sahut-Barnola, Isabelle, Pointud, Jean-Christophe, Martinez, Antoine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190936/
https://ncbi.nlm.nih.gov/pubmed/21808064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.218016
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