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High-content tripartite split-GFP cell-based assays to screen for modulators of small GTPase activation

The human Ras superfamily of small GTPases controls essential cellular processes such as gene expression and cell proliferation. As their deregulation is widely associated with human cancer, small GTPases and their regulatory proteins have become increasingly attractive for the development of novel...

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Bibliografski detalji
Izdano u:J Cell Sci
Glavni autori: Koraïchi, Faten, Gence, Rémi, Bouchenot, Catherine, Grosjean, Sarah, Lajoie-Mazenc, Isabelle, Favre, Gilles, Cabantous, Stéphanie
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818064/
https://ncbi.nlm.nih.gov/pubmed/29192060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.210419
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