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High-content tripartite split-GFP cell-based assays to screen for modulators of small GTPase activation

The human Ras superfamily of small GTPases controls essential cellular processes such as gene expression and cell proliferation. As their deregulation is widely associated with human cancer, small GTPases and their regulatory proteins have become increasingly attractive for the development of novel...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Koraïchi, Faten, Gence, Rémi, Bouchenot, Catherine, Grosjean, Sarah, Lajoie-Mazenc, Isabelle, Favre, Gilles, Cabantous, Stéphanie
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5818064/
https://ncbi.nlm.nih.gov/pubmed/29192060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.210419
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