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In vivo Effects in Melanoma of ROCK Inhibition-Induced FasL Overexpression
Ectopic Fas-ligand (FasL) expression in tumor cells is responsible for both tumor escape through tumor counterattack of Fas-positive infiltrating lymphocytes and tumor rejection though inflammatory and immune responses. We have previously shown that RhoA GTPase and its effector ROCK negatively contr...
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| 出版年: | Front Oncol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500923/ https://ncbi.nlm.nih.gov/pubmed/26236689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00156 |
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