In vivo Effects in Melanoma of ROCK Inhibition-Induced FasL Overexpression

Ectopic Fas-ligand (FasL) expression in tumor cells is responsible for both tumor escape through tumor counterattack of Fas-positive infiltrating lymphocytes and tumor rejection though inflammatory and immune responses. We have previously shown that RhoA GTPase and its effector ROCK negatively contr...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Teiti, Iotefa, Florie, Bertrand, Pich, Christine, Gence, Rémi, Lajoie-Mazenc, Isabelle, Rochaix, Philippe, Favre, Gilles, Tilkin-Mariamé, Anne-Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500923/
https://ncbi.nlm.nih.gov/pubmed/26236689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00156
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