Melanoma-expressed CD70 is involved in invasion and metastasis

BACKGROUND: CD70 is a costimulatory molecule of the tumour necrosis factor family expressed in activated immune cells and some solid tumours. In lymphocytes CD70 triggers T cell-mediated cytotoxicity and mitogen-activated protein kinase phosphorylation. METHODS: We evaluated the expression of CD70 i...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Pich, Christine, Sarrabayrouse, Guillaume, Teiti, Iotefa, Mariamé, Bernard, Rochaix, Philippe, Lamant, Laurence, Favre, Gilles, Maisongrosse, Véronique, Tilkin-Mariamé, Anne-Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716537/
https://ncbi.nlm.nih.gov/pubmed/26671750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.412
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