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Melanoma Expressed-CD70 Is Regulated by RhoA and MAPK Pathways without Affecting Vemurafenib Treatment Activity

CD70 is a costimulatory molecule member of the Tumor Necrosis Factor family that is expressed on activated immune cells. Its ectopic expression has been described in several types of cancer cells including lymphomas, renal cell carcinomas and glioblastomas. We have recently described its expression...

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Publicat a:PLoS One
Autors principals: Pich, Christine, Teiti, Iotefa, Sarrabayrouse, Guillaume, Gallardo, Franck, Gence, Rémi, Tilkin-Mariamé, Anne-Françoise
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734704/
https://ncbi.nlm.nih.gov/pubmed/26828592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148095
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