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Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth

PURPOSE: The Epstein–Barr virus (EBV)-associated cancer nasopharyngeal carcinoma (NPC) is rare in Europe and North America but is a real public health problem in some regions of the world, such as southern Asia, North Africa, and for Inuit populations. Due to the anatomy and location of the nasophar...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Gallardo, Franck, Mariamé, Bernard, Gence, Remi, Tilkin-Mariamé, Anne-Francoise
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6135081/
https://ncbi.nlm.nih.gov/pubmed/30233143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S172538
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