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Conformational Heterogeneity and the Affinity of Substrate Molecular Recognition by Cytochrome P450cam
The broad and variable substrate specificity of cytochrome P450 enzymes makes them a model system for studying the determinants of protein molecular recognition. The archetypal cytochrome P450cam (P450cam) is a relatively specific P450, a feature once attributed to the high rigidity of its active si...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816979/ https://ncbi.nlm.nih.gov/pubmed/28581729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00238 |
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