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Dynamics underlying hydroxylation selectivity of cytochrome P450cam

Structural heterogeneity and the dynamics of the complexes of enzymes with substrates can determine the selectivity of catalysis; however, fully characterizing how remains challenging as heterogeneity and dynamics can vary at the spatial level of an amino acid residue and involve rapid timescales. W...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Ramos, Sashary, Mammoser, Claire C., Thibodeau, Katherine E., Thielges, Megan C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008267/
https://ncbi.nlm.nih.gov/pubmed/33545101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.01.027
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