A Role of the Putidaredoxin COOH-terminus in P-450(cam) (Cytochrome m) Hydroxylations

Methylene hydroxylation by cytochrome P-450(cam) (cytochrome m) can be resolved into four distinct steps: substrate addition, m(o) → m(os); reduction, m(os) → m(rs); dioxygen addition, m(rs) → m(O(2))(rs); followed by a second putidaredoxin (Pseudomonas putida ferredoxin)-mediated reduction and prod...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Sligar, S. G., Debrunner, P. G., Lipscomb, J. D., Namtvedt, M. J., Gunsalus, I. C.
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1974
Subjects:	Biological Sciences: Biochemistry
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4530269/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.10.3906
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