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A Role of the Putidaredoxin COOH-terminus in P-450(cam) (Cytochrome m) Hydroxylations

Methylene hydroxylation by cytochrome P-450(cam) (cytochrome m) can be resolved into four distinct steps: substrate addition, m(o) → m(os); reduction, m(os) → m(rs); dioxygen addition, m(rs) → m(O(2))(rs); followed by a second putidaredoxin (Pseudomonas putida ferredoxin)-mediated reduction and prod...

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Bibliographic Details
Main Authors: Sligar, S. G., Debrunner, P. G., Lipscomb, J. D., Namtvedt, M. J., Gunsalus, I. C.
Format: Artigo
Language:Inglês
Published: 1974
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC434294/
https://ncbi.nlm.nih.gov/pubmed/4530269
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