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Conformational Change Induced by Putidaredoxin Binding to Ferrous CO-ligated Cytochrome P450cam Characterized by 2D IR Spectroscopy

The importance of conformational dynamics to protein function is now well-appreciated. An outstanding question is whether they are involved in the effector role played by putidaredoxin (Pdx) in its reduction of the O(2) complex of cytochrome P450cam (P450cam), an archetypical member of the cytochrom...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Ramos, Sashary, Basom, Edward J., Thielges, Megan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243089/
https://ncbi.nlm.nih.gov/pubmed/30483514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00094
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