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Conformational Change Induced by Putidaredoxin Binding to Ferrous CO-ligated Cytochrome P450cam Characterized by 2D IR Spectroscopy

The importance of conformational dynamics to protein function is now well-appreciated. An outstanding question is whether they are involved in the effector role played by putidaredoxin (Pdx) in its reduction of the O(2) complex of cytochrome P450cam (P450cam), an archetypical member of the cytochrom...

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Библиографические подробности
Опубликовано в: :Front Mol Biosci
Главные авторы: Ramos, Sashary, Basom, Edward J., Thielges, Megan C.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243089/
https://ncbi.nlm.nih.gov/pubmed/30483514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00094
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