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Reconciling conformational heterogeneity and substrate recognition in cytochrome P450
Cytochrome P450, the ubiquitous metalloenzyme involved in detoxification of foreign components, has remained one of the most popular systems for substrate-recognition process. However, despite being known for its high substrate specificity, the mechanistic basis of substrate-binding by archetypal sy...
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| Vydáno v: | Biophys J |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Biophysical Society
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8204291/ https://ncbi.nlm.nih.gov/pubmed/33675756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.040 |
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