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Reconciling conformational heterogeneity and substrate recognition in cytochrome P450

Cytochrome P450, the ubiquitous metalloenzyme involved in detoxification of foreign components, has remained one of the most popular systems for substrate-recognition process. However, despite being known for its high substrate specificity, the mechanistic basis of substrate-binding by archetypal sy...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Dandekar, Bhupendra R., Ahalawat, Navjeet, Mondal, Jagannath
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8204291/
https://ncbi.nlm.nih.gov/pubmed/33675756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.02.040
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