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Methylene Oxidation of Alkyl Sulfates by Cytochrome P450(BM-3) and a Role for Conformational Selection in Substrate Recognition

Cytochrome P450(BM-3) (P450(BM-3)) is a flavoprotein reductase-heme fusion protein from the bacterium Bacillus megaterium that has been well-characterized in many biophysical aspects. Although the enzyme is known to catalyze the hydroxylation of medium and long-chain fatty acids at high rates, no de...

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Enregistré dans:
Détails bibliographiques
Publié dans:ACS Catal
Auteurs principaux: Guengerich, F. Peter, Fekry, Mostafa I.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317952/
https://ncbi.nlm.nih.gov/pubmed/34327041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.0c00677
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