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Protein Dynamics in Cytochrome P450 Molecular Recognition and Substrate Specificity using 2D IR Vibrational Echo Spectroscopy

Cytochrome (cyt) P450s hydroxylate a variety of substrates that can differ widely in their chemical structure. The importance of these enzymes in drug metabolism and other biological processes has motivated the study of the factors that enable their activity on diverse classes of molecules. Protein...

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Bibliografiske detaljer
Main Authors: Thielges, Megan C., Chung, Jean K., Fayer, Michael D.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063108/
https://ncbi.nlm.nih.gov/pubmed/21348488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109168h
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