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Substrate binding and protein conformational dynamics measured by 2D-IR vibrational echo spectroscopy

Enzyme structural dynamics play a pivotal role in substrate binding and biological function, but the influence of substrate binding on enzyme dynamics has not been examined on fast time scales. In this work, picosecond dynamics of horseradish peroxidase (HRP) isoenzyme C in the free form and when li...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Finkelstein, Ilya J., Ishikawa, Haruto, Kim, Seongheun, Massari, Aaron M., Fayer, M. D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1815234/
https://ncbi.nlm.nih.gov/pubmed/17296942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610027104
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