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Substrate binding and protein conformational dynamics measured by 2D-IR vibrational echo spectroscopy
Enzyme structural dynamics play a pivotal role in substrate binding and biological function, but the influence of substrate binding on enzyme dynamics has not been examined on fast time scales. In this work, picosecond dynamics of horseradish peroxidase (HRP) isoenzyme C in the free form and when li...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815234/ https://ncbi.nlm.nih.gov/pubmed/17296942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610027104 |
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