Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows

No immunogen to date has reliably elicited broadly neutralizing antibodies (bnAbs) to HIV in humans or animal models. Advances in the design of immunogens (BG505 SOSIP) that antigenically mimic the HIV envelope glycoprotein (Env)(1) have improved the elicitation of potent isolate-specific Ab respons...

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Podrobná bibliografie
Vydáno v:Nature
Hlavní autoři: Sok, Devin, Le, Khoa M., Vadnais, Melissa, Saye-Francisco, Karen, Jardine, Joseph G., Torres, Jonathan, Berndsen, Zachary T., Kong, Leopold, Stanfield, Robyn, Ruiz, Jennifer, Ramos, Alejandra, Liang, Chi-Hui, Chen, Patricia L., Criscitiello, Michael F., Mwangi, Waithaka, Wilson, Ian A., Ward, Andrew B., Smider, Vaughn V., Burton, Dennis R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812458/
https://ncbi.nlm.nih.gov/pubmed/28726771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature23301
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