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A Broad Role for Cysteines in Bovine Antibody Diversity

Ab diversity in most vertebrates results from the assortment of amino acid side chains on CDR loops formed through V(D)J recombination. Cows (Bos taurus) have a low combinatorial diversity potential because of a small number of highly homologous V, D, and J gene segments. Despite this, a subset of t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunohorizons
Hauptverfasser: Haakenson, Jeremy K., Deiss, Thaddeus C., Warner, Gabrielle F., Mwangi, Waithaka, Criscitiello, Michael F., Smider, Vaughn V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366855/
https://ncbi.nlm.nih.gov/pubmed/31619454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1900058
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