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A Broad Role for Cysteines in Bovine Antibody Diversity

Ab diversity in most vertebrates results from the assortment of amino acid side chains on CDR loops formed through V(D)J recombination. Cows (Bos taurus) have a low combinatorial diversity potential because of a small number of highly homologous V, D, and J gene segments. Despite this, a subset of t...

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Detalhes bibliográficos
Publicado no:Immunohorizons
Main Authors: Haakenson, Jeremy K., Deiss, Thaddeus C., Warner, Gabrielle F., Mwangi, Waithaka, Criscitiello, Michael F., Smider, Vaughn V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366855/
https://ncbi.nlm.nih.gov/pubmed/31619454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1900058
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