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Cyclic-GMP elevating agents suppress polyposis in Apc(Min) mice by targeting the preneoplastic epithelium
The cGMP signaling axis has been implicated in the suppression of intestinal cancers but the inhibitory mechanism and the extent to which this pathway can be targeted remains poorly understood. The present study has tested the effect of cGMP-elevating agents on tumorigenesis in the Apc(Min/+) mouse...
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| Publicat a: | Cancer Prev Res (Phila) |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811348/ https://ncbi.nlm.nih.gov/pubmed/29301746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0267 |
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