cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium

Signaling through cGMP has therapeutic potential in the colon, where it has been implicated in the suppression of colitis and colon cancer. In this study, we tested the ability of cGMP and type 2 cGMP-dependent protein kinase (PKG2) to activate forkhead box O (FoxO) in colon cancer cells and in the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Wang, Rui, Islam, Bianca N., Bridges, Allison, Sharman, Sarah K., Hu, Muhan, Hou, Yali, Somanath, Payaningal R., Venable, Laine, Singh, Nagendra, Kim, Sangmi, Sridhar, Subbaramiah, Hofmann, Franz, Browning, Darren D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389370/
https://ncbi.nlm.nih.gov/pubmed/27998725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.10.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados