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Sildenafil suppresses Inflammation-driven Colorectal Cancer in mice
Intestinal cyclic guanosine monophosphate (cGMP) signaling regulates epithelial homeostasis and has been implicated in the suppression of colitis and colon cancer. In this study, we investigated the cGMP-elevating ability of the phosphodiesterase-5 (PDE5) inhibitor sildenafil to prevent disease in t...
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| Publicado no: | Cancer Prev Res (Phila) |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5530733/ https://ncbi.nlm.nih.gov/pubmed/28468928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0015 |
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