Adenomatous Polyposis Coli (APC) Is Essential for Maintaining the Integrity of the Seminiferous Epithelium

Sertoli cells provide the microenvironment necessary for germ cell development and spermatogenesis; disruption of Sertoli cell morphology or function can lead to germ cell aplasia, which is observed in testicular dysgenesis syndrome. Mutation of the adenomatous polyposis coli (APC) gene has been ass...

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Bibliographic Details
Main Authors: Tanwar, Pradeep S., Zhang, LiHua, Teixeira, Jose M.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2011
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182425/
https://ncbi.nlm.nih.gov/pubmed/21816903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-0057
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