Adenomatous Polyposis Coli (APC) Is Essential for Maintaining the Integrity of the Seminiferous Epithelium

Sertoli cells provide the microenvironment necessary for germ cell development and spermatogenesis; disruption of Sertoli cell morphology or function can lead to germ cell aplasia, which is observed in testicular dysgenesis syndrome. Mutation of the adenomatous polyposis coli (APC) gene has been ass...

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Autores principales: Tanwar, Pradeep S., Zhang, LiHua, Teixeira, Jose M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2011
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182425/
https://ncbi.nlm.nih.gov/pubmed/21816903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-0057
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