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Adenomatous Polyposis Coli (APC) Is Essential for Maintaining the Integrity of the Seminiferous Epithelium

Sertoli cells provide the microenvironment necessary for germ cell development and spermatogenesis; disruption of Sertoli cell morphology or function can lead to germ cell aplasia, which is observed in testicular dysgenesis syndrome. Mutation of the adenomatous polyposis coli (APC) gene has been ass...

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Hlavní autoři: Tanwar, Pradeep S., Zhang, LiHua, Teixeira, Jose M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182425/
https://ncbi.nlm.nih.gov/pubmed/21816903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-0057
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