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Adenomatous Polyposis Coli (APC) Is Essential for Maintaining the Integrity of the Seminiferous Epithelium

Sertoli cells provide the microenvironment necessary for germ cell development and spermatogenesis; disruption of Sertoli cell morphology or function can lead to germ cell aplasia, which is observed in testicular dysgenesis syndrome. Mutation of the adenomatous polyposis coli (APC) gene has been ass...

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Autori principali: Tanwar, Pradeep S., Zhang, LiHua, Teixeira, Jose M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182425/
https://ncbi.nlm.nih.gov/pubmed/21816903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-0057
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