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Chemoprevention of Familial Adenomatous Polyposis by Bromo-noscapine (EM011) in the Apc(Min/+) Mouse Model
Germline mutation of the tumor suppressor gene, adenomatous polyposis coli (APC), is responsible for familial adenomatous polyposis (FAP) with nearly 100% risk for colon cancer at an early age. Although FAP is involved in only 1% of all colon cancer cases, over 80% of sporadic cancers harbor somatic...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362662/ https://ncbi.nlm.nih.gov/pubmed/22052467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.27344 |
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