PRIMARY CHEMOPREVENTION OF FAMILIAL ADENOMATOUS POLYPOSIS WITH SULINDAC

BACKGROUND: Familial adenomatous polyposis is caused by a germ-line mutation in the adenomatous polyposis coli gene and is characterized by the development of hundreds of colorectal adenomas and, eventually, colorectal cancer. Nonsteroidal antiinflammatory drugs can cause regression of adenomas, but...

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Auteurs principaux: Giardiello, Francis M., Yang, Vincent W., Hylind, Linda M., Krush, Anne J., Petersen, Gloria M., Trimbath, Jill D., Piantadosi, Steven, Garrett, Elizabeth, Geiman, Deborah E., Hubbard, Walter, Offerhaus, G. Johan A., Hamilton, Stanley R.
Format: Artigo
Langue:Inglês
Publié: 2002
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225537/
https://ncbi.nlm.nih.gov/pubmed/11932472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa012015
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