Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma

Glioblastoma is the most malignant and lethal subtype brain tumors with high risk of recurrence and therapeutic resistance. Emerging evidence has indicated that glycogen synthesis kinase 3 (GSK3)β plays oncogenic roles in multiple tumor types; however, the underlying mechanisms remain largely unknow...

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Veröffentlicht in:Int J Oncol
Hauptverfasser: Yang, Yong, Lei, Tiantian, Du, Suya, Tong, Rongsheng, Wang, Hailian, Yang, Jiao, Huang, Juan, Sun, Minghan, Wang, Yi, Dong, Zhi
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807039/
https://ncbi.nlm.nih.gov/pubmed/29328365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4237
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