Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma

Glioblastoma is the most malignant and lethal subtype brain tumors with high risk of recurrence and therapeutic resistance. Emerging evidence has indicated that glycogen synthesis kinase 3 (GSK3)β plays oncogenic roles in multiple tumor types; however, the underlying mechanisms remain largely unknow...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Oncol
Main Authors: Yang, Yong, Lei, Tiantian, Du, Suya, Tong, Rongsheng, Wang, Hailian, Yang, Jiao, Huang, Juan, Sun, Minghan, Wang, Yi, Dong, Zhi
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807039/
https://ncbi.nlm.nih.gov/pubmed/29328365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4237
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