Nuclear GSK3β induces DNA double-strand break repair by phosphorylating 53BP1 in glioblastoma

Glioblastoma is the most malignant and lethal subtype brain tumors with high risk of recurrence and therapeutic resistance. Emerging evidence has indicated that glycogen synthesis kinase 3 (GSK3)β plays oncogenic roles in multiple tumor types; however, the underlying mechanisms remain largely unknow...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Yang, Yong, Lei, Tiantian, Du, Suya, Tong, Rongsheng, Wang, Hailian, Yang, Jiao, Huang, Juan, Sun, Minghan, Wang, Yi, Dong, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807039/
https://ncbi.nlm.nih.gov/pubmed/29328365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4237
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