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Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling

The tissue factor (TF) pathway serves both hemostasis and cell signaling, but how cells control these divergent functions of TF remains incompletely understood. TF is the receptor and scaffold of coagulation proteases cleaving protease-activated receptor 2 (PAR2) that plays pivotal roles in angiogen...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Rothmeier, Andrea S., Liu, Enbo, Chakrabarty, Sagarika, Disse, Jennifer, Mueller, Barbara M., Østergaard, Henrik, Ruf, Wolfram
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5805488/
https://ncbi.nlm.nih.gov/pubmed/29246902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-02-768218
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