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The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)

The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for all glycosphingolipids (GSL), which are essential for proper cell function. Interestingly, the UGCG is also overexpressed in several cancer ty...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Wegner, Marthe-Susanna, Gruber, Lisa, Mattjus, Peter, Geisslinger, Gerd, Grösch, Sabine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801679/
https://ncbi.nlm.nih.gov/pubmed/29409484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4084-4
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