Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes

Ceramides are sphingolipids with defined acyl chain lengths, which are produced by corresponding ceramide synthases (CerS1-6). In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), the ablation of CerS2 suppresses EAE-pathology by reducing neutrophil migrati...

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Publicado en:Sci Rep
Autores principales: Kurz, Jennifer, Barthelmes, Julia, Blum, Leonard, Ulshöfer, Thomas, Wegner, Marthe-Susanna, Ferreirós, Nerea, Roser, Luise, Geisslinger, Gerd, Grösch, Sabine, Schiffmann, Susanne
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345911/
https://ncbi.nlm.nih.gov/pubmed/30679689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37342-8
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