UGCG influences glutamine metabolism of breast cancer cells

UDP-glucose ceramide glucosyltransferase (UGCG) is the key enzyme in glycosphingolipid (GSL) metabolism by being the only enzyme that generates glucosylceramide (GlcCer) de novo. Increased UGCG synthesis is associated with pro-cancerous processes such as increased proliferation and multidrug resista...

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Publicado no:Sci Rep
Main Authors: Schömel, Nina, Hancock, Sarah E., Gruber, Lisa, Olzomer, Ellen M., Byrne, Frances L., Shah, Divya, Hoehn, Kyle L., Turner, Nigel, Grösch, Sabine, Geisslinger, Gerd, Wegner, Marthe-Susanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6821892/
https://ncbi.nlm.nih.gov/pubmed/31666638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52169-7
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