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The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)

The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for all glycosphingolipids (GSL), which are essential for proper cell function. Interestingly, the UGCG is also overexpressed in several cancer ty...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Wegner, Marthe-Susanna, Gruber, Lisa, Mattjus, Peter, Geisslinger, Gerd, Grösch, Sabine
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801679/
https://ncbi.nlm.nih.gov/pubmed/29409484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4084-4
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