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Screening Fusion Tags for Improved Recombinant Protein Expression in E. coli with the Expresso(®) Solubility and Expression Screening System

The simplicity, speed, and low cost of bacterial culture make E. coli the system of choice for most initial trials of recombinant protein expression. However, many heterologous proteins are either poorly expressed in bacteria, or are produced as incorrectly folded, insoluble aggregates that lack the...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Protoc Protein Sci
Hauptverfasser: Steinmetz, Eric, Auldridge, Michele
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791521/
https://ncbi.nlm.nih.gov/pubmed/29091274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpps.39
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