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Screening Fusion Tags for Improved Recombinant Protein Expression in E. coli with the Expresso(®) Solubility and Expression Screening System

The simplicity, speed, and low cost of bacterial culture make E. coli the system of choice for most initial trials of recombinant protein expression. However, many heterologous proteins are either poorly expressed in bacteria, or are produced as incorrectly folded, insoluble aggregates that lack the...

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Detalhes bibliográficos
Publicado no:Curr Protoc Protein Sci
Main Authors: Steinmetz, Eric, Auldridge, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791521/
https://ncbi.nlm.nih.gov/pubmed/29091274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpps.39
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