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Emerging Insights into Noncanonical Inflammasome Recognition of Microbes
Inflammasomes are cytosolic multi-molecular complexes that sense intracellular microbial danger signals and metabolic perturbations. Inflammasome activation leads to the activation of caspase-1 and the release of pro-inflammatory cytokines IL-1β and IL-18 accompanied by cell death. An inflammasome-b...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5790197/ https://ncbi.nlm.nih.gov/pubmed/29017836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.003 |
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