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Emerging Insights into Noncanonical Inflammasome Recognition of Microbes

Inflammasomes are cytosolic multi-molecular complexes that sense intracellular microbial danger signals and metabolic perturbations. Inflammasome activation leads to the activation of caspase-1 and the release of pro-inflammatory cytokines IL-1β and IL-18 accompanied by cell death. An inflammasome-b...

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Bibliografische gegevens
Gepubliceerd in:J Mol Biol
Hoofdauteurs: Russo, Ashley J., Behl, Bharat, Banerjee, Ishita, Rathinam, Vijay A.K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790197/
https://ncbi.nlm.nih.gov/pubmed/29017836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.003
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